Lab Findings Support the Concept that Reducing Neuroinflammation Could Help Fight Alzheimer’s
Scientists from DZNE, University Hospital Bonn (UKB) and the University of Bonn provide new evidence that preventing brain inflammation is a promising approach for the treatment of Alzheimer’s disease. Their findings, based on studies in cell culture, mice and tissue samples from patients, may contribute to the development of more effective therapies. They are published in the scientific journal “Immunity”. 
Invitation to the award of an honorary doctorate to Prof. Sharon Ruth Lewin on the 5th of February, 2025
The event will take place on February 5th, 2025, at 11:00 a.m. in the DZNE lecture hall and last about two hours.
MULTIPLIERS: Where Everyone Wins
Around 1,500 schoolchildren from six EU countries have been engaged in intensive study of some of the challenges currently facing the world in the company of natural science experts. After completing each module on a different topic, they have been acting as “multipliers,” sharing their knowledge and experiences with their family, friends and classmates. Three schools from Bonn took part.
„Bone2Gene“ erhält eine Million Euro
Das Projekt „Bone2Gene“ von Forschenden der Universität Bonn und des Universitätsklinikums Bonn (UKB) erhält eine Förderung des Programms GO-Bio initial vom Bundesministerium für Bildung und Forschung in Höhe von 1.000.000 Euro. Damit geht das Team nun in die sogenannte Machbarkeitsphase über und bereitet die Vermarktung seines Produktes vor. Zuvor hatte das Projekt bereits eine erste Förderung für die Sondierungsphase erhalten und die Marktfähigkeit des Produktes getestet. „Bone2Gene“ setzt Künstliche Intelligenz ein, um die Erkennung und Diagnose von genetischen Knochenerkrankungen, sogenannten Skelettdysplasien, zu vereinfachen.
Rise up! Award 2024 presented to two Bonn researchers
Recently, the Boehringer Ingelheim Foundation presented two Rise up! Awards 2024 to a scientist from Bonn.
From text to structured information securely with AI
Artificial intelligence (AI) and above all large language models (LLMs), which also form the basis for ChatGPT, are increasingly in demand in hospitals. However, patient data must always be protected. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have now been able to show that local LLMs can help structure radiological findings in a privacy-safe manner, with all data remaining at the hospital. They compared various LLMs on public reports without data protection and on data-protected reports. Commercial models that require data transfer to external servers showed no advantage over local, data protection-compliant models. The results have now been published in the journal "Radiology".
Inflammatory diseases influence the course of hair loss
Asthma, atopic dermatitis or Hashimoto's thyroiditis as concomitant diseases are risk factors for clinical features associated with a poor prognosis in circular hair loss, also known as alopecia areata (AA). In patients with three atopic diseases, namely atopic dermatitis, asthma and rhinitis, the average age of onset of AA is about ten years earlier than in patients without chronic inflammatory comorbidities. This has now been established by researchers from the University Hospital Bonn (UKB) and the University of Bonn in a large cohort study of affected patients. Their results have now been published in the journal "Allergy".
Colored nuclei reveal cellular key genes
The identification of genes involved in diseases is one of the major challenges of biomedical research. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have developed a method that makes their identification much easier and faster: they light up genome sequences in the cell nucleus. In contrast to complex screenings using established methods, the NIS-Seq method can be used to investigate the genetic determinants of almost any biological process in human cells. The study has now been published in Nature Biotechnology.
Wird geladen