Researchers from the Universities of Bonn and Cologne observe the danger sensor NLRP3

Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances. Researchers from the Universities of Bonn and Cologne were able to show that inflammatory reactions of an important sensor protein proceed in a specific spatial direction. This finding has the potential to conceivably stop inflammation at the "growing end", and thus bring chronic inflammatory diseases to a halt. The study has now been published in the journal "Science Advances".

Honoring Outstanding and Dedicated Early-Career Researchers

The Universitätsgesellschaft Bonn (UGB) presented its prestigious prizes for superlative doctoral theses and its Initiative Award for student involvement during its spring matinée. The ceremony returned to being held in person in the Arithmeum.

Enzyme prevents brain activity from getting out of control

The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team from Australia, have identified a mechanism that plays an important role in this. In cultured cells, this mechanism alters the synaptic coupling of neurons and thus stimulus transmission and processing. If it is disrupted, diseases such as epilepsy, schizophrenia or autism may be the result. The findings are published in the journal Cell Reports.

New approach against chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies." These nanobodies enabled them to dissolve molecular complexes in tissue that normally activate the immune system. The nanobodies produced may in future help to slow down unwanted inflammatory reactions that cause diseases such as arthritis or neurodegeneration. The study is published in the journal EMBO Molecular Medicine.

Food as therapy - nutritional patient care

It is well known: Healthy food promotes healing. Nevertheless, many hospitals pay little attention to nutrition. A nationwide unique teaching project at the University Hospital Bonn (UKB) now aims to bring together medical students in their internship year (PJler) and nutritionists in their master's studies. The goal of the interprofessional training series, which started on April 13: Healthy food - as well as the prescribed medication - is an important therapy factor. Furthermore, nutritional medicine is to become an interprofessional subject at the UKB.

Excellent Performance in the QS Subject Rankings

The University of Bonn is able to report fresh improvements in the QS World University Rankings by subject. Judged to be one of the best of its kind in Germany, our Mathematics Department also enjoys a leading international reputation as 49th in the world. Other of our subjects were also able to improve their international standing.

State of NRW promotes Research Networks

The North Rhine-Westphalian state government is supporting five outstanding research networks in pioneering research fields with a total of 81.2 million euros. Among them is "iBehave" under the leadership of the University of Bonn, which is being funded with around 20 million euros. The university of excellence is also involved in NRW-CANTAR.

Understanding the brain with artificial intelligence

The University of Bonn has once again received excellent reinforcement: Dominik Bach now fills a so-called Hertz Chair, which is designed to combine disciplines in a unique way. The internationally renowned psychologist, physician and mathematician will establish a new focus at the interface between neuroscience, psychiatry and computer science in the Transdisciplinary Research Area "Life and Health". He and his team want to use mathematical methods to decipher how the brain works. To this end, they analyze human behavior in extreme situations.

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